That’s why managing dandruff often takes more than just a shampoo (though it’s still a great place to start). Supportive conditioners, leave-ins, and barrier-repair formulas can help calm irritation, rebalance the scalp, and keep flakes from making a comeback between washes. Ahead, the best dandruff treatments derms recommend when flakes show up uninvited.
Frequently Asked Questions
Best Overall: Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole
Nizoral
Anti-Dandruff Shampoo with 1% Ketoconazole
Why it’s worth it: When it comes to treating dandruff, dermatologists often turn to ketoconazole, “which is an antifungal that inhibits an enzyme key to yeast growth,” as a first line of defense, says Dr. De La Cruz. “Usually I start with a ketoconazole-based shampoo like Nizoral Anti-Dandruff Shampoo with 1% ketoconazole, given that studies show ketoconazole to be slightly better tolerated than other ingredients,” says Dr. De La Cruz. Ketoconazole works by controlling Malassezia yeast that fuels dandruff, helping calm flaking, itching, and irritation at the source instead of simply rinsing flakes away. If an over-the-counter formula doesn’t do the trick, Dr. De La Cruz notes she’ll prescribe a 2% ketoconazole shampoo for severe dandruff. Bonus: Nizoral has a fresh, clean scent that makes it feel more pleasant to use regularly.
Tester feedback from Allure senior commerce director Shanna Shipin
“Eczema doesn’t just plague my skin—it hits me with an intensely itchy(!!) and flaky scalp. Needing a gentle yet effective solution, my doctor long ago suggested I use Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, and it’s helped me manage the snowy flakes of dandruff over the years. Nizoral has helped me tackle suspected fungal acne breakouts on my forehead, too. Those tiny acne bumps hate to see the blue shampoo coming.” —Shanna Shipin, shopping director
More to know
- Key ingredient: 1% ketoconazole
- Fragrance-free: no
Best Shampoo: Vichy Dercos Selenium Sulfide Anti-Dandruff Shampoo
Vichy Laboratories
Dercos Selenium Sulfide Anti-Dandruff Shampoo
Why it’s worth it: If your dandruff comes with thicker, oilier scales, selenium sulfide is often the next move. “Selenium sulfide works very well and feels comfortable, is not overly drying, and works quickly,” says Dr. De La Cruz. Like ketoconazole, it targets the fungus behind flakes, but via a different angle: “Unlike ketoconazole that blocks the enzyme for yeast production, selenium sulfide prevents the division of fungal cells,” she explains. Vichy Dercos is formulated with 0.6% micronized selenium sulfide, allowing the active to distribute more evenly across the scalp and fight flakes at the source. Supporting ingredients like niacinamide, glycerin, salicylic acid, and menthol help calm itch, loosen buildup, and leave the scalp feeling refreshed. “Oftentimes I have patients alternate between this and a ketoconazole shampoo to get the best results,” she says.
More to know
- Key ingredients: 0.6% micronized selenium sulfide, niacinamide, glycerin
- Fragrance-free: no
Best Conditioner: CeraVe Hydrating Anti-Dandruff Conditioner
CeraVe
Hydrating Anti-Dandruff Conditioner
Why it’s worth it: Most dandruff treatments focus on flakes alone, but CeraVe Hydrating Anti-Dandruff Conditioner takes care of the scalp, too (no surprise if you already know the brand for its gentle, barrier-supporting skincare). This formula relies on 0.5% pyrithione zinc, a milder antifungal that helps keep dandruff-causing yeast in check while being gentle enough for regular use, paired with ceramides, niacinamide, and hyaluronic acid to reinforce the scalp barrier, soothe irritation, and keep hair feeling soft and easy to detangle. “The ceramides offer a very comfortable conditioning experience to help detangle the hair, while the zinc pyrithione further helps to treat dandruff,” says Dr. De La Cruz. It’s a nourishing pick when you want ongoing flake control without the dryness that can come with stronger antifungals like ketoconazole or selenium sulfide, which are often better suited for short-term treatment.
More to know
- Key ingredients: 0.5% pyrithione zinc, hyaluronic acid, ceramides, niacinamide
- Fragrance-free: yes
Best for Textured Hair: Cécred Scalp Refreshing Spray
Cécred
Scalp Refreshing Spray
Why it’s worth it: Cécred’s Scalp Refreshing Spray is made with braids, wigs, and extensions in mind—making it perfect for those in-between wash days when your scalp still needs care. While it doesn’t contain medicated ingredients to treat dandruff at the source, it helps take the edge off itchiness and discomfort that often come with flakes, especially when buildup or style-related tension is involved. The lightweight, no-rinse spray features a targeted nozzle that breaks down buildup and dead skin without disturbing your style, while menthol delivers a subtle, instantly soothing cooling effect. Ingredients like Lactobacillus ferment, ceramides, and honey help calm and comfort the scalp, making it an easy daily refresh for protective styles and extensions.
“I inherited my flaky scalp from my father. Just like him, I used medicated dandruff shampoos for most of my life. Then I tried the Cécred Detoxifying Shampoo. The silky later doesn’t dry out my hair like pyrithione zinc. It smells faintly of peppermint oil and cools my scalp with menthol (and it has a purplish blue color, whish is just cool). But what keeps me going back is that it keeps itchy patches away for two solid weeks. For an even better boost, I spritz my scalp with the Cécred Scalp Refreshing Spray before hopping in the shower. The spray was formulated to stop the itch when wearing protective styles like braids, but I find it a great pre-shampoo treatment to dislodge any debris or flakes before I wash. It has a tingling sensation that lasts then the detoxifying shampoo finishes the job.” —Jessica Cruel, Allure editor in chief
More to know
- Key ingredients: phytoferment, honey, ceramides, menthol, Lactobacillus
- Fragrance-free: no
Best Serum: Jupiter Restoring Serum
Jupiter
Restoring Serum
Why it’s worth it: Wash-off dandruff treatments don’t always get enough time on your skin, which is where a leave-in scalp treatment like Jupiter Restoring Serum comes in. Designed to stay put, the lightweight serum delivers 0.125% zinc pyrithione to help control the yeast linked to flakes and irritation between washes. It’s backed by salicylic acid to gently loosen buildup, plus niacinamide and panthenol to calm irritation and support the scalp barrier. Soothing botanicals (like aloe, green tea, and Lactobacillus yeast ferment) help take down redness and itch, while lightweight oils add comfort without greasiness. It absorbs quickly and easily—you can use it up to four times a day—and is ideal for anyone rotating dandruff actives or spacing out wash days while still wanting consistent flake control.
“Dandruff treatments always have a medicinal, off-putting smell—but not this one. It smells clean as it soothes my flaky, itchy scalp.” —Jesa Marie Calaor, Allure senior editor
More to know
- Key ingredients: 0.125% zinc pyrithione, glycerin, safflower seed oil, salicylic acid, Lactobacillus ferment, aloe, green tea, salicylic acid
- Fragrance-free: yes
Best for Oily Scalps: Neutrogena T/Sal Therapeutic Dandruff Shampoo
Neutrogena
T/Sal Therapeutic Dandruff Shampoo
Why it’s worth it: Most people assume flakes automatically mean a dry scalp, but classic dandruff is usually tied to excess oil, not a lack of it. The yeast that drives dandruff (Malassezia) feeds on sebum, so when oil builds up, flaking and itch often follow. Neutrogena T/Sal Therapeutic Dandruff Shampoo uses 3% salicylic acid “to break down thick, greasy scales and loosen stubborn buildup,” making it especially helpful for dandruff, seborrheic dermatitis, and even psoriasis-related flakes, says Dr. De La Cruz. Unlike antifungal shampoos that target yeast directly, T/Sal focuses on clearing the excess skin and oil that keep flakes coming back. The fragrance-free formula cleanses thoroughly, giving even sensitive scalps a chance to reset while minimizing skin irritation.
More to know
- Key ingredient: 3% salicylic acid
- Fragrance-free: yes
Best for Dry Scalps: Dove Derma Dryness and Itch Relief Anti-Dandruff Shampoo
Dove
Derma Dryness and Itch Relief Anti-Dandruff Shampoo
Why it’s worth it: If your flakes are small, white, and powdery, it’s easy to jump straight to “dandruff,” but that combo usually means dry scalp, especially if things feel tight rather than itchy or inflamed. Dove Derma Dryness and Itch Relief Anti-Dandruff Shampoo focuses on what dry, itchy scalps need: gentle, moisturizing cleansing that helps soften and reduce the shedding of dry skin. It uses 1% pyrithione zinc to help calm dryness-related itch and keep your scalp feeling comfortable. Then the formula backs that up with coconut oil, shea butter, glycerin, and sunflower seed oil to condition, smooth, and help the scalp feel more balanced.
More to know
- Key ingredients: 1% pyrithione zinc, coconut oil, shea butter
- Fragrance-free: no
Best Scalp Exfoliator: Nioxin Scalp Purifying Exfoliator
Nioxin
Scalp Purifying Exfoliator
Why it’s worth it: Dandruff lives its best life in an environment of buildup and excess oil, which is why targeted exfoliation can make such a difference. Nioxin’s Scalp Purifying Exfoliator is designed to clear away what keeps flakes coming back, giving the scalp a deeper reset than shampoo alone. “This product is a creamy exfoliant that helps lift buildup and excess oil off the scalp without irritation,” says Fatima Fahs, MD, a board-certified dermatologist based in Southfield, Michigan. Used on dry hair before shampooing, the rinse-out treatment relies on lactic, tartaric, and benzoic acids to loosen dead skin, unclog follicles, and rebalance the scalp—key steps for managing dandruff and flakiness. To prevent over-drying, the formula is buffered with shea butter for moisture, while peppermint oil delivers a cooling, calming effect.
More to know
- Key ingredients: peppermint oil, shea butter, lactic acid, tartaric acid, benzoic acid
- Fragrance-free: no
Frequently Asked Questions
Is dandruff the same as dry scalp?
“When people see white scales and flakes on their scalp, they think it’s dandruff, but it’s actually dry skin,” says Dr. De La Cruz. True dandruff usually appears as larger white-to-yellow flakes with a slightly oily texture that stick to the scalp and hair rather than falling away like fine powder.
Can you get rid of dandruff?
You can’t get rid of dandruff for good, but you can usually manage it very well, depending on what’s causing it. “Whether dandruff can be ‘cured’ or just managed will depend on the type and cause of dandruff that the person has,” says Dr. De La Cruz. For common skin conditions such as seborrheic dermatitis or psoriasis, the goal is to maintain control and minimize flares. On the other hand, she notes that dandruff caused by product buildup or contact dermatitis can often be resolved completely by removing the trigger. In other words, some flakes are a short-term fix, while others require a longer-term game plan.
What ingredients should I look for in an anti-dandruff shampoo?
When shopping for anti-dandruff hair care products, it helps to look for ingredients that target the root cause of flakes, not just the symptoms. “Active ingredients to look for in anti-dandruff shampoo include yeast-focused ingredients like zinc pyrithione, selenium sulfide, or ketoconazole,” says Dr. De La Cruz, since these help control the yeast linked to dandruff. She also notes the value of exfoliating ingredients—“like salicylic acid or glycolic acid”—which help loosen buildup and lift flakes so they can rinse away more easily. The right formula depends on whether yeast, buildup, or both are driving your dandruff.
Meet the experts
- Julie de la Cruz, MD, a board-certified dermatologist and co-founder of Miami Dermatology & Surgery based in Miami
- Fatima Fahs, MD, a board-certified dermatologist based in Southfield, Michigan
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When Allure tests a product, our editors look at it from every angle in an effort to best serve you. We review ingredients, scrutinize brand claims, and, when necessary, examine peer-reviewed scientific and medical studies. In addition to testing each and every product that’s included in each and every review, we rely on experts who shape their fields, including dermatology, cosmetic chemistry, and medicine, to help us vet the ingredients and formulas.
For our list of the best dandruff treatments, we considered each product’s performance across five primary categories: product ingredients and efficacy, packaging, fragrance, texture, and product wear. Every product was determined to have excelled in each category by our editorial team of in-house writers and editors, as well as contributors, along with special consideration from dermatologists. To learn more about our reporting and testing processes, read our complete reviews process and methodology page.
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